Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.70 |
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553544 | 1.00 | NR5A1 (0.70) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| SCHEMBL10062560 | 1.00 | NR5A1 (0.70) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| SCHEMBL13064200 | 1.00 | NR5A1 (0.70) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| 1-Ethoxy-4-Pentoxybenzene SCHEMBL27243485 | 0.98 | NR5A1 (0.67) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| Methyl Alcohol SCHEMBL28166727 | 0.96 | NR5A1 (0.71) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| SCHEMBL10943900 | 0.93 | NR5A1 (0.79) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL8936597 | 0.93 | NR5A1 (0.79) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL14984021 | 0.93 | NQO1 (0.74) | NR5A1NQO1LTA4HKDM4EALDH1A1 | |
| SCHEMBL11095674 | 0.93 | NR5A1 (0.79) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL2829024 | 0.93 | NR5A1 (0.79) | NR5A1LTA4HTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | NR5A1 997/4885NQO1 364/4885LTA4H 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.