Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511120 | 0.90 | GAA (0.81) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL16511117 | 0.89 | GAA (0.83) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL825962 | 0.87 | GAA (0.64) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL11985668 | 0.85 | GAA (0.66) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL2822477 | 0.83 | KMT2A (0.76) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL16511119 | 0.81 | ALDH1A1 (0.73) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL16511225 | 0.80 | ALDH1A1 (0.75) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL2822487 | 0.77 | GAA (0.58) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL7644013 | 0.76 | GAA (0.71) | GAASMN1; SMN2CYP2D6POLBKMT2A | |
| SCHEMBL5476362 | 0.76 | ALDH1A1 (0.64) | GAASMN1; SMN2CYP2D6POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3012254-A1 | BIPHENYL DERIVATIVE AND ITS USE FOR TREATING PULMONARY DISORDERS | Theravance Respiratory Company, LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2246345-A1 | BIPHENYL DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | Theravance Inc (US) | 2010-11-03 | — | — | EP | disclosed |