Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | BCR | P11274 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13022962 | 0.91 | IKBKB (0.47) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL13066001 | 0.84 | TOP1 (0.46) | MEN1KMT2ARXFP1 | |
| SCHEMBL13023160 | 0.82 | IKBKB (0.44) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL2416002 | 0.80 | KCNK3 (0.59) | PDGFRBKDRMEN1KMT2APTPN11 | |
| SCHEMBL13023068 | 0.78 | PTPN11 (0.60) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL13023126 | 0.76 | IKBKB (0.56) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL13023070 | 0.75 | LMNA (0.47) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL13023127 | 0.75 | KCNK3 (0.50) | IKBKBLCKTEKPDGFRBKDR | |
| SCHEMBL13023102 | 0.75 | IKBKB (0.55) | IKBKBLCKTEKABL1BCR | |
| SCHEMBL13023107 | 0.75 | NPC1 (0.54) | IKBKBPDGFRBKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | IKBKB 1528/4885LCK 3869/4885TEK 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.