Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 11/20 | 0.72 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | GALR3 | O60755 | 1/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | STAT6 | P42226 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.62 |
| ▸ | GAPDH | P04406 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419279 | 1.00 | ADK (0.72) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL17816342 | 1.00 | ADK (0.72) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14429016 | 0.99 | ADK (0.71) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14428970 | 0.99 | ADK (0.71) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14429014 | 0.99 | ADK (0.71) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14643919 | 0.91 | ADK (0.66) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL17816346 | 0.88 | ADK (0.61) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL17816351 | 0.88 | ADK (0.61) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14274456 | 0.88 | ADK (0.73) | ADKDOT1LALDH1A1HTTNPC1 | |
| SCHEMBL14429130 | 0.88 | ADK (0.59) | ADKDOT1LALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135520-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | WO | disclosed |