Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649108 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL21782410 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL5682469 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL13184474 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL14853781 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL19326322 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL13486944 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL13672338 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL15095564 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL13151549 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135520-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | WO | disclosed |