Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.59 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978978 | 0.88 | TRPV1 (0.62) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL30605278 | 0.84 | TRPV1 (0.66) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL25938725 | 0.84 | TRPV1 (0.66) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL9979424 | 0.82 | ABCG2 (0.54) | TRPV1THRB | |
| SCHEMBL688080 | 0.82 | PLK1 (0.53) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL4811926 | 0.81 | S1PR1 (0.57) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL77257 | 0.81 | S1PR1 (0.60) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL11340641 | 0.81 | S1PR1 (0.60) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL10762816 | 0.80 | S1PR1 (0.58) | S1PR1S1PR4S1PR5S1PR3PLK1 | |
| SCHEMBL11747076 | 0.80 | S1PR1 (0.53) | S1PR1S1PR4S1PR5S1PR3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | S1PR1 2915/4885S1PR4 3947/4885S1PR5 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.