SCHEMBL9979424

SCHEMBL9979424

CCCc1cccc(NC(=O)c2cc(C(=O)Nc3cccc(CCC)c3)cc(C(=O)Nc3cccc(CCC)c3)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIN2B Q13224 1/20 0.54
GRIN2C Q14957 1/20 0.54
GRIN3A Q8TCU5 1/20 0.54
SIGMAR1 Q99720 1/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
RXFP1 Q9HBX9 1/20 0.53
TRPV1 Q8NER1 2/20 0.52
THRB P10828 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
NR1H4 Q96RI1 1/20 0.51
NLRP3 Q96P20 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978978 0.91 TRPV1 (0.62) KMT2AMEN1RXFP1TRPV1THRB
SCHEMBL17683821 0.88 TRPV1 (0.54) ABCG2KMT2AMEN1TRPV1ITGB3
SCHEMBL9979193 0.87 ALDH1A1 (0.62) KMT2AMEN1RXFP1THRBNR1H4
SCHEMBL1696311 0.84 MEN1 (0.70) KMT2AMEN1RXFP1THRBNR1H4
SCHEMBL1696515 0.83 AOC3 (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL27644958 0.83 GRIN2D (0.56) ABCG2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13065985 0.82 S1PR1 (0.59) TRPV1THRB
SCHEMBL24690443 0.82 POLB (0.63) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8883356 0.82 SIGMAR1 (0.62) ABCG2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9978841 0.81 TRPV1 (0.58) ABCG2TRPV1NR1H4NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed