Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | XBP1 | P17861 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874820 | 0.87 | MAPT (0.74) | MAPTNPC1LMNAGSTO1RAB9A | |
| Protoapigenone SCHEMBL13066080 | 0.81 | KMT2A (1.00) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL15395297 | 0.78 | HTT (0.76) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL30931536 | 0.74 | PTGS1 (0.55) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL30931535 | 0.74 | PTGS1 (0.55) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL2874541 | 0.73 | MAPT (0.71) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL15245959 | 0.73 | FLT3 (0.74) | MAPTNPC1LMNARAB9AKMT2A | |
| SCHEMBL24882669 | 0.72 | EGFR (0.78) | MAPTNPC1LMNAKMT2APTGS2 | |
| SCHEMBL13445691 | 0.71 | KMT2A (0.80) | MAPTNPC1LMNAGSTO1RAB9A | |
| SCHEMBL3185003 | 0.70 | MAOB (0.62) | MAPTNPC1LMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842721-B2 | Composition for treating cancer cells and synthetic method for the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-30 | — | — | US | disclosed |
| US-20090054516-A1 | COMPOSITION FOR TREATING CANCER CELLS AND SYNTHETIC METHOD FOR THE SAME | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054516-A1 | COMPOSITION FOR TREATING CANCER CELLS AND SYNTHETIC METHOD FOR THE SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HK2, HCCS | MAPT 4770/4885NPC1 1101/4885LMNA 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.