Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.80 |
| ▸ | MAPT | P10636 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | NPC1 | O15118 | 3/20 | 0.80 |
| ▸ | RAB9A | P51151 | 2/20 | 0.80 |
| ▸ | XBP1 | P17861 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protoapigenone SCHEMBL13066080 | 0.89 | KMT2A (1.00) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL15395253 | 0.81 | KMT2A (0.71) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL15395297 | 0.76 | HTT (0.76) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL2874820 | 0.75 | MAPT (0.74) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL2874541 | 0.72 | MAPT (0.71) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL13066079 | 0.71 | MAPT (0.67) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL15395350 | 0.71 | MAPT (0.57) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL22738310 | 0.69 | MEN1 (0.75) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL2427225 | 0.69 | KMT2A (0.54) | KMT2AMAPTLMNANPC1RAB9A | |
| SCHEMBL30931536 | 0.69 | PTGS1 (0.55) | KMT2AMAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062078-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND THE SIGNALING PATHWAY THEREOF | Yuan, Shyng-Shiou (TW) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062078-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND THE SIGNALING PATHWAY THEREOF | MAPK3, CASP3, MAPK4 | KMT2A 3972/4885MAPT 1999/4885LMNA 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.