Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962470 | 0.89 | HPGD (0.58) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5161794 | 0.84 | HPGD (0.56) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5162010 | 0.82 | HPGD (0.56) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5158404 | 0.81 | RAB9A (0.49) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5162389 | 0.81 | MEN1 (0.56) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5176341 | 0.81 | HPGD (0.51) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5176147 | 0.80 | HPGD (0.50) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5159057 | 0.80 | HPGD (0.53) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5161041 | 0.80 | HPGD (0.63) | HPGDTP53GLACTSDKCNA3 | |
| SCHEMBL5159245 | 0.79 | HPGD (0.55) | HPGDTP53GLACTSDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253328-A1 | Cycloalkyl inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-11-24 | — | — | EP | disclosed |