SCHEMBL13067378

SCHEMBL13067378

CCN1C(=S)N(CCCN)C(=O)/C1=C\C=C1/Oc2ccccc2N1CC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 13/20 0.58
KMT2A Q03164 13/20 0.58
MAPT P10636 12/20 0.58
ALDH1A1 P00352 10/20 0.58
MAPK1 P28482 7/20 0.58
HTT P42858 3/20 0.58
TDP1 Q9NUW8 2/20 0.45
TNNI3 P19429 1/20 0.45
TNNT2 P45379 1/20 0.45
TNNC1 P63316 1/20 0.45
NPC1 O15118 5/20 0.39
THRB P10828 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.36
KDM4E B2RXH2 3/20 0.34
HPGD P15428 2/20 0.34
POLB P06746 1/20 0.34
MDM2 Q00987 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22906177 0.89 MEN1 (0.58) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL10036037 0.89 MEN1 (0.58) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL13026075 0.84 MAPT (0.52) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL10036043 0.82 MAPT (0.59) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL7092891 0.82 MAPT (0.52) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL3835949 0.81 MAPT (0.52) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL7050730 0.81 MAPT (0.52) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL12572504 0.81 MEN1 (0.56) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL11336753 0.79 MAPK1 (0.59) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL13751809 0.79 ALDH1A1 (0.59) MEN1KMT2AMAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100276670-A1 PHOTOELECTRIC DEVICE, IMAGING DEVICE, AND PHOTOSENSOR FUJIFILM CORPORATION (JP) 2010-11-04 US disclosed