Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.59 |
| ▸ | RAB9A | P51151 | 13/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23079706 | 1.00 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL23079995 | 0.93 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL18583160 | 0.92 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL23079859 | 0.86 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL13621031 | 0.85 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL23079994 | 0.85 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL10125862 | 0.84 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL13067695 | 0.84 | SMN1; SMN2 (0.85) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL25796564 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL2250462 | 0.83 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126270-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) | 2010-11-04 | — | — | WO | disclosed |