Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763312 | 1.00 | DNM1 (0.48) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL22625454 | 1.00 | DNM1 (0.48) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL366647 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL985792 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL10155552 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL24044418 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL15211724 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL13601912 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL12844942 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 | |
| SCHEMBL4745188 | 0.97 | TSHR (0.46) | DNM1TSHRLMNATHRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129053-A2 | EGFR INHIBITORS AND METHODS OF TREATING DISORDERS | DANA FARBER CANCER INSTITUTE (US) | 2010-11-11 | — | — | WO | disclosed |