Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 5/20 | 0.36 |
| ▸ | METAP1 | P53582 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371837 | 0.86 | GRIN2D (0.40) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3371841 | 0.86 | GRIN2D (0.40) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27596043 | 0.86 | GRIN2D (0.40) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL3370440 | 0.84 | CNR1 (0.39) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL3370436 | 0.84 | CNR1 (0.39) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3374776 | 0.80 | CNR1 (0.42) | PPARGHTTNPSR1METAP1CNR1 | |
| SCHEMBL3372133 | 0.80 | CNR1 (0.42) | PPARGHTTNPSR1METAP1CNR1 | |
| SCHEMBL31570745 | 0.77 | HTT (0.48) | PPARGGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13068047 | 0.74 | PNMT (0.42) | GRIN1GRIN2BHTTSCN4ASLC6A2 | |
| Hydrochloric Acid SCHEMBL3374572 | 0.73 | PNMT (0.41) | GRIN1GRIN2BHTTSCN4ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-B1 | SUBSTITUTED AMIDES | MERCK SHARP & DOHME (US) | 2010-11-03 | — | — | EP | disclosed |