Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.73 |
| ▸ | PPARD | Q03181 | 14/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450961 | 0.85 | PPARG (0.80) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL206775 | 0.84 | PPARD (0.69) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450988 | 0.84 | PPARD (0.95) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450733 | 0.84 | PPARD (1.00) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10011429 | 0.81 | PPARD (0.62) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL15211310 | 0.81 | PPARD (0.64) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450581 | 0.80 | PPARG (0.77) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL31674239 | 0.79 | PPARD (0.59) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL13126358 | 0.79 | PPARG (0.84) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3451756 | 0.79 | PPARG (0.78) | PPARGPPARDFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248812-A2 | Fused cyclic compounds as GPR40 receptor modulators | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |