SCHEMBL31674239

SCHEMBL31674239

O=C(O)CC1COc2cc(F)ccc21

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 14/20 0.59
PPARG P37231 13/20 0.59
FFAR1 O14842 16/20 0.55
PPARA Q07869 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31674325 0.89 PPARD (0.49) PPARDPPARGFFAR1PPARA
SCHEMBL17061202 0.85 KDM4C (0.55) PPARDPPARG
SCHEMBL3003128 0.83 PPARG (0.60) PPARDPPARGFFAR1PPARA
SCHEMBL9979637 0.83 PPARG (0.60) PPARDPPARGFFAR1PPARA
SCHEMBL204645 0.83 PPARG (0.60) PPARDPPARGFFAR1PPARA
SCHEMBL15292428 0.82 FFAR1 (0.69) PPARDPPARGFFAR1PPARA
SCHEMBL4414880 0.82 PPARG (0.59) PPARDPPARGFFAR1PPARA
SCHEMBL15299338 0.82 FFAR1 (0.69) PPARDPPARGFFAR1PPARA
SCHEMBL10011520 0.82 PPARG (0.59) PPARDPPARGFFAR1PPARA
SCHEMBL15211310 0.81 PPARD (0.64) PPARDPPARGFFAR1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042760-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY ACONCAGUA BIO INC (US) 2026-02-12 US disclosed
US-12486269-B2 Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity ACONCAGUA BIO, INC. (US) 2025-12-02 US disclosed
US-20250257067-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY ACONCAGUA BIO, INC. 2025-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486269-B2 Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity IAPP, GIPR, SCTR PPARD 966/4885PPARG 209/4885FFAR1 107/4885
US-20260042760-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY NPY1R, CALCRL, SCTR PPARD 2119/4885PPARG 1026/4885FFAR1 126/4885
US-20250257067-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY IAPP, GIPR, SCTR PPARD 966/4885PPARG 209/4885FFAR1 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.