Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 6/20 | 0.66 |
| ▸ | DRD3 | P35462 | 6/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | HRH1 | P35367 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055963 | 0.93 | DRD1 (0.67) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL38652366 | 0.91 | DRD1 (0.69) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL30088530 | 0.90 | DRD1 (0.71) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL11806768 | 0.90 | DRD1 (0.71) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL28524068 | 0.90 | DRD1 (0.68) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL30350890 | 0.90 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL28615035 | 0.90 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL7272756 | 0.90 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| Bromide SCHEMBL7280018 | 0.89 | DRD1 (0.70) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| Bromide SCHEMBL11805167 | 0.88 | DRD1 (0.69) | DRD1DRD3ADRB2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976525-B1 | PIPERIDINE AND PIPERAZINE DERIVATIVES | MS SCIENCE CORP (JP) | 2010-11-03 | — | — | EP | disclosed |