Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652366 | 0.95 | DRD1 (0.69) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL7272756 | 0.93 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL28524068 | 0.93 | DRD1 (0.68) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL28615035 | 0.93 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL30350890 | 0.93 | DRD1 (0.72) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL13068844 | 0.93 | DRD1 (0.66) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| Bromide SCHEMBL7280018 | 0.92 | DRD1 (0.70) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL11811440 | 0.87 | ADRB2 (0.73) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL11806768 | 0.87 | DRD1 (0.71) | DRD1DRD3ADRB2SLC6A2SLC6A3 | |
| SCHEMBL30088530 | 0.87 | DRD1 (0.71) | DRD1DRD3ADRB2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135525-A1 | Carbondisulfide Derived Zwitterions | DALY THOMAS (US) | 2022-05-05 | — | — | US | disclosed |
| US-10975027-B2 | Carbondisulfide derived zwitterions | DALY THOMAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200331853-A1 | Carbondisulfide Derived Zwitterions | DALY THOMAS (US) | 2020-10-22 | — | — | US | disclosed |
| US-10696628-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190233372-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2019-08-01 | — | — | US | disclosed |
| US-10259783-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC | 2019-04-16 | — | — | US | disclosed |
| US-20170275248-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2017-09-28 | — | — | US | disclosed |
| US-9676709-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC | 2017-06-13 | — | — | US | disclosed |
| US-20170129853-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2017-05-11 | — | — | US | disclosed |
| US-9580385-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC | 2017-02-28 | — | — | US | disclosed |
| US-20150329486-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2015-11-19 | — | — | US | disclosed |
| US-20150246879-A1 | Carbondisulfide Derived Zwitterions | DALY THOMAS P (US) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129853-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20170275248-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20150329486-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-10259783-B2 | Carbondisulfide derived zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20220135525-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20200331853-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-10696628-B2 | Carbondisulfide derived zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20150246879-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-10975027-B2 | Carbondisulfide derived zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
| US-20190233372-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | DRD1 76/4885DRD3 141/4885ADRB2 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.