Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372831 | 0.88 | FGFR4 (0.46) | SRCFGFR4LRRK2XDH | |
| SCHEMBL3372252 | 0.82 | SRC (0.40) | SRCLRRK2XDHCYP11B1CYP11B2 | |
| SCHEMBL3373015 | 0.76 | CHEK1 (0.38) | LRRK2 | |
| SCHEMBL3373013 | 0.76 | CHEK1 (0.38) | LRRK2 | |
| SCHEMBL13068861 | 0.76 | CHEK1 (0.38) | LRRK2 | |
| SCHEMBL27668260 | 0.69 | LRRK2 (0.57) | SRCLRRK2XDH | |
| SCHEMBL13955657 | 0.68 | SRC (0.44) | SRCLRRK2XDHCYP11B1CYP11B2 | |
| SCHEMBL13955599 | 0.68 | SRC (0.42) | SRCFGFR4LRRK2XDH | |
| SCHEMBL16800086 | 0.65 | IMPDH2 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL3272833 | 0.65 | CSF1R (0.38) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869036-B1 | SUBSTITUTED 1,5-NAPHTHYRIDINE AZOLIDINONES AS CDK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2010-11-03 | — | — | EP | disclosed |