Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.52 |
| ▸ | WNT1 | P04628 | 12/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069257 | 0.86 | DYRK1A (0.51) | DYRK1AWNT1GSK3B | |
| SCHEMBL2086139 | 0.85 | DYRK1A (0.63) | DYRK1AWNT1GSK3B | |
| SCHEMBL2086280 | 0.85 | DYRK1A (0.63) | DYRK1AWNT1GSK3B | |
| SCHEMBL2087459 | 0.85 | DYRK1A (0.67) | DYRK1AWNT1GSK3B | |
| SCHEMBL2087658 | 0.85 | DYRK1A (0.67) | DYRK1AWNT1GSK3B | |
| SCHEMBL2087435 | 0.85 | DYRK1A (0.67) | DYRK1AWNT1GSK3B | |
| SCHEMBL13069184 | 0.84 | DYRK1A (0.73) | DYRK1AWNT1GSK3B | |
| SCHEMBL13069595 | 0.80 | GSK3B (0.58) | DYRK1AWNT1GSK3B | |
| SCHEMBL12514838 | 0.80 | DYRK1A (0.55) | DYRK1AWNT1GSK3B | |
| SCHEMBL13069622 | 0.80 | DYRK1A (0.55) | DYRK1AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742944-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2010-11-10 | — | — | EP | disclosed |