Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.42 |
| ▸ | PPARD | Q03181 | 17/20 | 0.42 |
| ▸ | PPARG | P37231 | 17/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376896 | 0.84 | PPARD (0.53) | PPARAPPARDPPARG | |
| SCHEMBL3375295 | 0.83 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL3377036 | 0.83 | PPARG (0.47) | PPARAPPARDPPARGCYP2C9TSHR | |
| SCHEMBL13069647 | 0.81 | PPARG (0.46) | PPARAPPARDPPARGCYP2C9TSHR | |
| SCHEMBL3378784 | 0.80 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL3379784 | 0.78 | PPARD (0.46) | PPARAPPARDPPARGCYP2C9TSHR | |
| SCHEMBL3376214 | 0.78 | PPARG (0.51) | PPARAPPARDPPARG | |
| SCHEMBL3410208 | 0.78 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL3376815 | 0.77 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL13069652 | 0.76 | PPARA (0.48) | PPARAPPARDPPARGCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796665-B1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK SHARP & DOHME (US) | 2010-11-17 | — | — | EP | disclosed |