Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196011 | 1.00 | CTSK (0.50) | CTSKCTSSITGB3ITGA2BMEN1 | |
| SCHEMBL863894 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL863895 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL3773280 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL6036315 | 0.89 | CTSK (0.51) | CTSKCTSSITGB3ITGA2BMEN1 | |
| SCHEMBL3432850 | 0.89 | CTSK (0.51) | CTSKCTSSITGB3ITGA2BMEN1 | |
| SCHEMBL3431559 | 0.89 | CTSK (0.51) | CTSKCTSSITGB3ITGA2BMEN1 | |
| SCHEMBL1820405 | 0.88 | CTSK (0.52) | CTSKCTSSMEN1KMT2AATM | |
| SCHEMBL11506791 | 0.88 | CTSK (0.49) | CTSKCTSSMEN1KMT2AATM | |
| SCHEMBL5129671 | 0.87 | CTSK (0.47) | CTSKCTSSITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401433-B1 | AZOLE ACID DERIVATIVES, ALONE OR IN COMBINATION, FOR TREATING DIABETES AND DYSLIPIDEMIAS; AND FOR TREATING MALIGNANT DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2010-11-10 | — | — | EP | disclosed |
| US-7452907-B2 | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-18 | — | — | US | disclosed |