Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394762 | 1.00 | HIF1A (0.52) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL9073247 | 0.89 | HIF1A (0.55) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL8859711 | 0.89 | HIF1A (0.55) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL12266195 | 0.89 | HIF1A (0.55) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL15144388 | 0.89 | NFKB1 (0.47) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL10350563 | 0.89 | CYP3A4 (0.47) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL11702557 | 0.88 | NFKB1 (0.47) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL11702567 | 0.88 | NFKB1 (0.47) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL12265813 | 0.87 | NFKB1 (0.46) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL10394061 | 0.87 | CYP3A4 (0.58) | HIF1ACYP3A4NR3C1PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122096-A1 | PROCESS FOR OBTAINING FLUOROMETHOLONE AND INTERMEDIATES THEREFOR | CRYSTAL PHARMA, S.L.U. (ES) | 2010-10-28 | — | — | WO | disclosed |