Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307000 | 1.00 | P2RX3 (0.39) | P2RX3PLA2G2AADAMTS4ADAMTS5MEN1 | |
| SCHEMBL1306621 | 0.92 | P2RX3 (0.42) | P2RX3PLA2G2AADAMTS4ADAMTS5MEN1 | |
| SCHEMBL1306629 | 0.92 | P2RX3 (0.42) | P2RX3PLA2G2AADAMTS4ADAMTS5MEN1 | |
| SCHEMBL1306290 | 0.91 | P2RX3 (0.42) | P2RX3ADAMTS4ADAMTS5MEN1KMT2A | |
| SCHEMBL29488466 | 0.91 | P2RX3 (0.42) | P2RX3ADAMTS4ADAMTS5MEN1KMT2A | |
| SCHEMBL1306288 | 0.91 | P2RX3 (0.42) | P2RX3ADAMTS4ADAMTS5MEN1KMT2A | |
| SCHEMBL1307082 | 0.90 | P2RX3 (0.42) | P2RX3CNR2DRD4ALDH1A1PREP | |
| SCHEMBL1307079 | 0.90 | P2RX3 (0.42) | P2RX3CNR2DRD4ALDH1A1PREP | |
| SCHEMBL1307946 | 0.88 | P2RX3 (0.52) | P2RX3DRD4 | |
| SCHEMBL1307948 | 0.88 | P2RX3 (0.52) | P2RX3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |