Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25677702 | 0.98 | USP2 (0.55) | USP2HTTSPHK1PRKD3PRKCG | |
| SCHEMBL129126 | 0.98 | USP2 (0.55) | USP2HTTSPHK1PRKD3PRKCG | |
| SCHEMBL128032 | 0.92 | — | — | |
| SCHEMBL128128 | 0.81 | — | — | |
| SCHEMBL96285 | 0.77 | USP2 (0.54) | USP2HTTSPHK1PRKD3PRKCG | |
| SCHEMBL18068161 | 0.77 | HTT (0.33) | USP2HTT | |
| SCHEMBL11267791 | 0.77 | USP2 (0.54) | USP2HTTSPHK1PRKD3PRKCG | |
| SCHEMBL29300033 | 0.77 | HSD17B10 (0.48) | USP2HTTMEN1THRBKMT2A | |
| Fluoromethane SCHEMBL14348297 | 0.75 | THRB (0.59) | USP2HTTSPHK1MEN1THRB | |
| SCHEMBL4489928 | 0.75 | USP2 (0.57) | USP2HTTSPHK1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | USP2 3605/4885HTT 3059/4885SPHK1 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.