Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314945 | 0.82 | CYP2C9 (0.43) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL9980188 | 0.78 | MAPK13 (0.48) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL15274610 | 0.78 | MAPK13 (0.48) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL15747168 | 0.77 | CYP2C9 (0.45) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL1317926 | 0.77 | CYP2C9 (0.45) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL1317924 | 0.77 | CYP2C9 (0.45) | MAPK13MAPK12MAPK11MAPK14CYP2C9 | |
| SCHEMBL15395786 | 0.75 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL18501415 | 0.75 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL18534591 | 0.74 | KMT2A (0.35) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15346266 | 0.74 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |