Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349950 | 0.82 | KMT2A (0.39) | KMT2ASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL20218565 | 0.79 | LPL (0.36) | — | |
| SCHEMBL15585595 | 0.79 | LPL (0.36) | — | |
| SCHEMBL4727696 | 0.78 | CDC7 (0.43) | ALDH1A1LMNA | |
| SCHEMBL15362839 | 0.78 | CDC7 (0.43) | ALDH1A1LMNA | |
| SCHEMBL15773761 | 0.77 | ABL1 (0.38) | KMT2AKDM4E | |
| SCHEMBL14914689 | 0.77 | ABL1 (0.38) | KMT2AKDM4E | |
| SCHEMBL14915403 | 0.77 | ABL1 (0.38) | KMT2AKDM4E | |
| SCHEMBL2449358 | 0.76 | ABL1 (0.38) | KMT2A | |
| SCHEMBL18727386 | 0.76 | CHRNA7 (0.32) | SMN1; SMN2ALDH1A1NPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850075-B1 | PIPERAZINE-PIPERIDINE COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-02-22 | — | — | EP | disclosed |