⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100975 | 0.97 | — | — | |
| SCHEMBL2051798 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL1189958 | 0.90 | — | — | |
| Methylamine SCHEMBL27953780 | 0.87 | — | — | |
| Carbamic Acid SCHEMBL3170790 | 0.85 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23615942 | 0.83 | — | — | |
| SCHEMBL27293688 | 0.77 | ALOX5 (0.41) | — | |
| SCHEMBL4551459 | 0.75 | ALOX5 (0.47) | — | |
| SCHEMBL16611567 | 0.74 | — | — | |
| SCHEMBL2256325 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014902-B2 | MYC G-quadruplex stabilizing small molecules and their use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-05-25 | — | — | US | disclosed |
| EP-3215499-B1 | IMINOSUGARS USEFUL FOR THE TREATMENT OF VIRAL DISEASES | EMERGENT VIROLOGY LLC (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20200308128-A1 | MYC G-QUADRUPLEX STABILIZING SMALL MOLECULES AND THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2020-10-01 | — | — | US | disclosed |
| EP-3012258-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS | Gilead Sciences, Inc. (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2585467-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2016-03-02 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-7618971-B2 | Mitotic kinesin inhibitors | MERCK & CO. INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20080027058-A1 | Mitotic Kinesin Inhibitors | MERCK SHARP & DOHME CORP. | 2008-01-31 | — | — | US | disclosed |