⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22364671 | 0.77 | — | — | |
| SCHEMBL10140833 | 0.77 | — | — | |
| SCHEMBL8748467 | 0.77 | — | — | |
| SCHEMBL20348273 | 0.75 | — | — | |
| SCHEMBL8749473 | 0.73 | — | — | |
| SCHEMBL13071166 | 0.72 | NOS3 (0.31) | — | |
| SCHEMBL13338040 | 0.72 | NOS3 (0.31) | — | |
| SCHEMBL24754251 | 0.72 | — | — | |
| SCHEMBL12438204 | 0.72 | — | — | |
| SCHEMBL13464739 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2907816-B1 | Condensed imidazolylimidazoles as antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-06-13 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |