Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464785 | 0.86 | KDM4E (0.56) | AAK1SCN10AMEN1KMT2ANPC1 | |
| SCHEMBL2756682 | 0.83 | RAB9A (0.61) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL18462650 | 0.80 | AAK1 (0.52) | AAK1SCN10AMEN1KMT2AHTT | |
| SCHEMBL26427165 | 0.79 | CYP1A2 (0.67) | AAK1SCN10AMEN1KMT2ANPC1 | |
| SCHEMBL2705606 | 0.78 | KDM4E (0.65) | AAK1SCN10AALDH1A1KDM4EHTT | |
| SCHEMBL15463298 | 0.78 | KMT2A (0.50) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2457137 | 0.78 | RAB9A (0.67) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9263421 | 0.76 | KDM4E (0.71) | AAK1SCN10AMEN1KMT2ANPC1 | |
| SCHEMBL21609998 | 0.76 | SCN10A (0.60) | SCN10AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL18462597 | 0.75 | KDM4E (0.52) | AAK1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |