Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070772 | 0.91 | AR (0.45) | ARPGRCNR2 | |
| SCHEMBL3419674 | 0.87 | AR (0.57) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL13071085 | 0.87 | AR (0.42) | ARPGRCNR2 | |
| SCHEMBL13070688 | 0.86 | AR (0.56) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL13326316 | 0.86 | AR (0.49) | ARPGRCNR2 | |
| SCHEMBL13070583 | 0.85 | AR (0.41) | ARPGR | |
| SCHEMBL13070578 | 0.85 | AR (0.55) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL13326443 | 0.84 | AR (0.47) | ARPGRCNR2 | |
| SCHEMBL3291849 | 0.84 | CNR2 (0.45) | ARPGRCNR2 | |
| SCHEMBL13070775 | 0.83 | AR (0.53) | ARCYP2C19ABCB11ALBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154181-A1 | RGD-CONTAINING PEPTIDOMIMETICS AND USES THEREOF | STEBA BIOTECH S.A. (LU) | 2014-06-05 | — | — | US | disclosed |
| US-7834063-B2 | 4-[(Cyclopropylmethyl)(2-{[4-(1,1-dimethylethyl)phenyl]oxy}ethyl)amino]-2-(trifluoromethyl)benzonitrile; modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors; osteoporosis, muscle wasting,endometriosis, cardiovascular disease; breast, uterine cancer, prostatic hyperplasia | GLAXOSMITHKLINE LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-20080255124-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140154181-A1 | RGD-CONTAINING PEPTIDOMIMETICS AND USES THEREOF | GRPR, VIP, PROKR1 | AR 3008/4885CYP2C19 3828/4885ABCB11 2914/4885 |
| US-20080255124-A1 | Chemical Compounds | NR3C2, NR5A1, NR3C1 | AR 4/4885CYP2C19 236/4885ABCB11 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.