Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.46 |
| ▸ | ACACA | Q13085 | 12/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898467 | 0.90 | ACACB (0.51) | ACACBACACABACE1CDK4CCND1 | |
| SCHEMBL13070822 | 0.90 | ACACB (0.48) | ACACBACACABACE1CDK4CCND1 | |
| SCHEMBL13071068 | 0.87 | ALDH1A1 (0.39) | ACACBACACAMEN1POLBKMT2A | |
| SCHEMBL13096250 | 0.84 | ACACB (0.50) | ACACBACACABACE1 | |
| SCHEMBL14372083 | 0.84 | ACACB (0.52) | ACACBACACABACE1 | |
| SCHEMBL14372081 | 0.84 | ACACB (0.52) | ACACBACACABACE1 | |
| SCHEMBL14372088 | 0.83 | ACACB (0.47) | ACACBACACABACE1 | |
| SCHEMBL3684010 | 0.82 | ACACB (0.47) | ACACBACACABACE1 | |
| SCHEMBL14129223 | 0.82 | ACACB (0.45) | ACACBACACABACE1 | |
| SCHEMBL1899703 | 0.82 | ACACB (0.47) | ACACBACACABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253207-A1 | Substituted phenyl acetic acid esters | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2216316-A1 | Phenyl acetic acid derivatives | Bayer CropScience Aktiengesellschaft (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2216317-A1 | Phenyl acetic acid halogenides | Bayer CropScience AG (DE) | 2010-08-11 | — | — | EP | disclosed |