Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275550 | 0.85 | CYP3A4 (0.37) | CYP2C19ALDH1A1 | |
| SCHEMBL10068148 | 0.81 | ESR1 (0.31) | — | |
| SCHEMBL8849196 | 0.71 | ESR1 (0.36) | — | |
| SCHEMBL17830164 | 0.71 | — | — | |
| SCHEMBL18545720 | 0.70 | GAA (0.35) | CYP2C19 | |
| SCHEMBL316918 | 0.69 | PPARG (0.34) | CYP2C19ALDH1A1 | |
| SCHEMBL10396703 | 0.68 | CA9 (0.31) | — | |
| SCHEMBL38982 | 0.68 | CYP3A4 (0.33) | CYP2C19ALDH1A1MCOLN3 | |
| SCHEMBL3224833 | 0.68 | CYP3A4 (0.33) | CYP2C19ALDH1A1MCOLN3 | |
| SCHEMBL3798470 | 0.68 | CYP3A4 (0.33) | CYP2C19ALDH1A1MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130349-A1 | UV-CURING PROTECTIVE LAYER FOR THERMOPLASTIC SUBSTRATES | BAYER MATERIALSCIENCE AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| EP-1302309-B1 | Multi-layer, weatherable compositions and method of manufacture thereof | GEN ELECTRIC (US) | 2008-09-03 | — | — | EP | disclosed |