SCHEMBL8849196

SCHEMBL8849196

CC(=O)N1C(C)(C)CC(N2C(=O)C=CC2=O)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1815774 0.80 GAA (0.36) L3MBTL1KMT2A
SCHEMBL8849271 0.78 GSK3A (0.36)
SCHEMBL697805 0.78 GSK3A (0.31) MAPK1
SCHEMBL10396703 0.76 CA9 (0.31) ESR1
SCHEMBL10579748 0.75
SCHEMBL10068148 0.74 ESR1 (0.31) ESR1
SCHEMBL2870659 0.74
SCHEMBL11316450 0.74 ESR1 (0.34) ESR1LMNAL3MBTL1MEN1RAB9A
SCHEMBL2688393 0.72 MAPK1 (0.45) LMNAL3MBTL1MEN1KMT2AMAPK1
SCHEMBL13072064 0.71 CYP2C19 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499581-B1 Stabilized polymer composition CIBA GEIGY AG (CH) 1997-07-09 EP disclosed
EP-0479725-B1 Stabilized styrene copolymers containing elastomer particles CIBA GEIGY AG (CH) 1995-04-26 EP disclosed
CN-1027071-C Process for preparing styrene copolymers or alpha-methylstyrene copolymers containing elastomer particles CIBA GEIGY AG (CH) 1994-12-21 CN disclosed
US-5288777-A Adding sterically hindered piperidines CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 EP disclosed
EP-0337431-B1 STABILIZED STYRENE COPOLYMER COMPRISING ELASTOMER PARTICLES CIBA-GEIGY AG (CH) 1993-06-23 EP disclosed
EP-0293871-B1 LIGHT STABILIZED, STARSHAPED MICROPARTICLES CIBA-GEIGY AG (CH) 1993-03-17 EP disclosed
US-5194465-A Photostability, graft polymers, unsaturated hindered amine modifier CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
EP-0499581-A1 Stabilized polymer composition CIBA-GEIGY AG (CH) 1992-08-19 EP disclosed
US-5135986-A Graft polymers of styrene or A-methylstyrene and a comonomer on a core of elastomer modified by a steric hindered unsaturated 2,2,6,6-tetramethylpiperidine compoune; photostability CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed
EP-0296391-A2 Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY AG (CH) 1988-12-28 EP disclosed
EP-0293871-A2 Light stabilized, starshaped microparticles CIBA-GEIGY AG (CH) 1988-12-07 EP disclosed
US-4294949-A ACRYLATES OR ACRYLAMIDES WHICH CARRY N-HETEROCYCLIC RINGS CIBA-GEIGY CORPORATION (US) 1981-10-13 US disclosed
US-4276401-A N-Heterocyclic substituted acryloyl polymeric compounds CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4210612-A LIGHT STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
EP-0010518-A1 Acrylic copolymers bearing N-heterocyclic side rings, their use, and process for their preparation CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0001840-A2 Stabilising mixtures, process for stabilising synthetic materials against light with these mixtures and synthetic materials so stabilised CIBA-GEIGY AG (CH) 1979-05-16 EP disclosed
EP-0000496-A1 Acrylic polymers substituted by N-heterocyclic rings and their use as light protection agents CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed