Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13051159 | 0.96 | LTA4H (0.56) | LTA4HKCNH2CXCR6 | |
| SCHEMBL745109 | 0.96 | LTA4H (0.56) | LTA4HKCNH2CXCR6 | |
| SCHEMBL12244441 | 0.85 | LTA4H (0.65) | LTA4HKCNH2CXCR6 | |
| SCHEMBL13051156 | 0.84 | LTA4H (0.72) | LTA4HKCNH2 | |
| SCHEMBL742387 | 0.84 | LTA4H (0.72) | LTA4HKCNH2 | |
| SCHEMBL1902477 | 0.82 | LTA4H (0.60) | LTA4HKCNH2CXCR6 | |
| SCHEMBL12245170 | 0.82 | LTA4H (0.60) | LTA4HKCNH2CXCR6 | |
| SCHEMBL13051160 | 0.82 | LTA4H (0.73) | LTA4HKCNH2 | |
| SCHEMBL742327 | 0.82 | LTA4H (0.73) | LTA4HKCNH2 | |
| SCHEMBL13051165 | 0.82 | LTA4H (0.73) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132599-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | WO | disclosed |