SCHEMBL13072401

SCHEMBL13072401

CN(C)C(=O)NNC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 4/20 0.38
▸ CARM1 Q86X55 5/20 0.37
▸ PDE4B Q07343 3/20 0.35
▸ KLKB1 P03952 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ TRPV1 Q8NER1 2/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13072902 0.94 F10 (0.37) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL13072403 0.93 F10 (0.36) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL12911614 0.91 PDE4B (0.38) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL10028786 0.90 F10 (0.39) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL13318535 0.89 PDE4B (0.39) F10PDE4BKLKB1KDM4EMEN1
SCHEMBL12559356 0.89 NOTUM (0.38) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL13318531 0.89 F10 (0.46) F10CARM1KLKB1KDM4ETRPV1
SCHEMBL13072524 0.89 CARM1 (0.36) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL782241 0.88 CARM1 (0.40) F10CARM1PDE4BKLKB1KDM4E
SCHEMBL951274 0.88 KLKB1 (0.40) F10CARM1PDE4BKLKB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 — — EP disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 — — US disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 — — US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 — — US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 — — US disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 F10 976/4885CARM1 2933/4885PDE4B 1981/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB F10 1737/4885CARM1 3298/4885PDE4B 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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