Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307290 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1CNR1PREP | |
| SCHEMBL1307286 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1CNR1PREP | |
| SCHEMBL1308301 | 0.88 | KMT2A (0.48) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1307271 | 0.87 | CNR1 (0.37) | MEN1KMT2AALDH1A1CNR1PREP | |
| SCHEMBL1307270 | 0.87 | CNR1 (0.37) | MEN1KMT2AALDH1A1CNR1PREP | |
| SCHEMBL1307002 | 0.87 | MEN1 (0.40) | MEN1KMT2AALDH1A1PREPADAMTS4 | |
| SCHEMBL1308082 | 0.86 | KMT2A (0.40) | MEN1KMT2AALDH1A1PREPSLC6A1 | |
| SCHEMBL1306121 | 0.86 | KMT2A (0.37) | MEN1KMT2AALDH1A1PREPSLC6A1 | |
| SCHEMBL29488473 | 0.86 | PREP (0.39) | MEN1KMT2AALDH1A1CNR1PREP | |
| SCHEMBL1306403 | 0.86 | PREP (0.39) | MEN1KMT2AALDH1A1CNR1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |