Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ABL1 | P00519 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | BCR | P11274 | 2/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730255 | 0.94 | ESR1 (0.65) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL19738377 | 0.91 | ESR1 (0.61) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL17547068 | 0.90 | ESR1 (0.65) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL28638329 | 0.86 | ESR1 (0.82) | ESR1KMT2AESR2LTA4HMMP3 | |
| SCHEMBL699012 | 0.86 | ESR1 (1.00) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL27269728 | 0.83 | ESR1 (0.56) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL28199055 | 0.82 | ESR1 (0.67) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL10455047 | 0.82 | ESR1 (0.67) | ESR1ESR2LTA4HMMP3BCL2L1 | |
| SCHEMBL30864393 | 0.81 | ESR1 (0.90) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL19845794 | 0.81 | ESR1 (0.90) | ESR1MEN1KMT2AABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838089-B2 | with biphenylcyclohexane-based skeleton; nematic at room temperature, improved response; paraelectric | SONY CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20090168009-A1 | with biphenylcyclohexane-based skeleton; nematic at room temperature, improved response; paraelectric | SONY CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |