Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076038 | 0.91 | EPHX2 (0.45) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL13076539 | 0.91 | EPHX2 (0.47) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL3798181 | 0.89 | EPHX2 (0.49) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL3715664 | 0.89 | EPHX2 (0.45) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL3716666 | 0.89 | EPHX2 (0.48) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL13076041 | 0.89 | MAPT (0.45) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL13075760 | 0.89 | EPHX2 (0.47) | ALDH1A1EPHX2HSD17B13 | |
| SCHEMBL13076532 | 0.88 | ALDH1A1 (0.50) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL13076717 | 0.87 | EPHX2 (0.55) | MAPTPOLBALDH1A1EPHX2PPARG | |
| SCHEMBL13075691 | 0.86 | POLB (0.40) | MAPTPOLBALDH1A1EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129848-A2 | 2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXAMIDES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-11 | — | — | WO | disclosed |