Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CDC25A | P30304 | 1/20 | 0.71 |
| ▸ | CDC25B | P30305 | 1/20 | 0.71 |
| ▸ | CDC25C | P30307 | 1/20 | 0.71 |
| ▸ | MPI | P34949 | 1/20 | 0.71 |
| ▸ | Q9HBH1 | 12/20 | 0.68 | |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 2/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076832 | 0.90 | MAPT (0.59) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL805350 | 0.89 | MAPT (0.64) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076408 | 0.88 | MAPT (0.68) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076843 | 0.85 | NR4A1 (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076855 | 0.85 | MAPT (0.58) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL801781 | 0.84 | MAPT (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL801214 | 0.83 | MAPT (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076497 | 0.82 | MAPT (0.50) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076861 | 0.82 | MAPT (0.51) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13076405 | 0.81 | NR4A1 (0.60) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129049-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-11-11 | — | — | WO | disclosed |