SCHEMBL130765

SCHEMBL130765

CCn1c2c(c3ccccc31)CC(=C1c3ccccc3-c3ccccc31)C=C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.40
▸ KDM4E B2RXH2 7/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ GSK3A P49840 2/20 0.39
▸ GSK3B P49841 2/20 0.39
▸ MAPT P10636 3/20 0.35
▸ HSD17B10 Q99714 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ NSD2 O96028 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HBB P68871 1/20 0.35
▸ HTR5A P47898 1/20 0.35
▸ CA1 P00915 3/20 0.35
▸ CA2 P00918 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21779759 0.70 ALDH1A1 (0.45) ALDH1A1KDM4ERAB9AGSK3AGSK3B
SCHEMBL13538135 0.70 ALDH1A1 (0.45) ALDH1A1KDM4ERAB9AMAPTHSD17B10
SCHEMBL3149549 0.68 KDM4E (0.48) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL17567426 0.67 GSK3B (0.51) ALDH1A1KDM4ERAB9AGSK3AGSK3B
SCHEMBL16229867 0.67 KDM4E (0.43) ALDH1A1KDM4ERAB9AMAPTHSD17B10
SCHEMBL130763 0.67 ALDH1A1 (0.39) ALDH1A1KDM4ERAB9AGSK3AGSK3B
SCHEMBL29963695 0.64 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL151563 0.64 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29360167 0.64 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL1459437 0.64 CA1 (0.71) ALDH1A1KDM4ERAB9AHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 — — US claimed
JP-52128373-A — — None — — JP disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 — — US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 — — US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 — — US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 — — US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 — — US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 — — US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 — — US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 — — US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 — — US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 — — US disclosed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 — — US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 — — US disclosed
US-4565759-A PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT RICOH CO., LTD. (JP) 1986-01-21 — — US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 — — US disclosed
US-4486519-A HIGH PHOTOSENSITYIVITY AND FLEXIBILITY RICOH COMPANY, LTD. (JP) 1984-12-04 — — US disclosed
US-4349616-A HIGHLY PHOTOSENSITIVE TO SHORT WAVELENGTHS; COPIERS; REPRODUCTION;LIGHT-SENSITIVE ELEMENTS RICOH CO., LTD. (JP) 1982-09-14 — — US disclosed
US-4134761-A CHARGE TRANSFER COMPOUNDS RICOH CO., LTD. (JP) 1979-01-16 — — US disclosed
JP-S52128373-A 3-(9-FLUORENYLIDENE) CARBAZOLE DERIVATIVES, THEIR PREPARATIONS, AND SENSITIZED MATERIAL FOR RICOH CO LTD 1977-10-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR ALDH1A1 1094/4885KDM4E 4009/4885RAB9A 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback