SCHEMBL1307669

SCHEMBL1307669

O=CC=Cc1cccc(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 2/20 0.60
CDK1 P06493 2/20 0.60
CDK4 P11802 2/20 0.60
CCNB1 P14635 2/20 0.60
CCND1 P24385 2/20 0.60
CCNB3 Q8WWL7 2/20 0.60
CYP1A2 P05177 3/20 0.58
CYP2C9 P11712 1/20 0.58
LMNA P02545 2/20 0.56
TRPA1 O75762 1/20 0.56
ALDH1A1 P00352 1/20 0.56
ALOX5 P09917 1/20 0.56
MAPK1 P28482 1/20 0.56
FBP1 P09467 2/20 0.55
MAOB P27338 4/20 0.50
CHAT P28329 1/20 0.50
CHRM5 P08912 1/20 0.50
RELA Q04206 1/20 0.49
XDH P47989 1/20 0.47
MAOA P21397 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1307668 1.00 CCNB2 (0.60) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL11471054 0.87 CYP1A2 (0.61) CYP1A2CYP2C9FBP1MAOBCHAT
SCHEMBL31114357 0.84 CDK4 (0.72) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL699364 0.82 CHAT (0.67) CYP1A2CYP2C9FBP1MAOBCHAT
SCHEMBL699365 0.82 CHAT (0.67) CYP1A2CYP2C9FBP1MAOBCHAT
SCHEMBL13291663 0.81 MAOB (0.61) CYP1A2CYP2C9LMNATRPA1ALDH1A1
SCHEMBL19452321 0.79 CYP1A2 (0.53) CYP1A2CYP2C9LMNAFBP1MAOB
SCHEMBL27958955 0.79 CYP1A2 (0.53) CYP1A2CYP2C9LMNAFBP1MAOB
SCHEMBL1759564 0.78 CHRM5 (0.54) CYP1A2CYP2C9FBP1MAOBCHAT
SCHEMBL9127026 0.78 AHR (0.50) CCNB2CDK1CDK4CCNB1CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529553-A Smoke-suppressing bird-repelling sand-containing fog sealing layer and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN claimed
CN-119522906-A Smoke-suppressing bird-repellent microcapsule, smoke-suppressing bird-repellent asphalt additive and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN claimed
CN-101492407-B Method for organic catalysis synthesis of beta-indole aldehyde UNIV LANZHOU 2011-02-09 CN claimed
CN-101492407-A Method for organic catalysis synthesis of beta-indole aldehyde UNIV LANZHOU (CN) 2009-07-29 CN claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
CN-119522906-A Smoke-suppressing bird-repellent microcapsule, smoke-suppressing bird-repellent asphalt additive and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN disclosed
CN-119529553-A Smoke-suppressing bird-repelling sand-containing fog sealing layer and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN disclosed
CN-118666731-A 2-Phenylindole derivative and preparation method and application thereof 东南大学 2024-09-20 CN disclosed
US-12050224-B2 Compounds useful as near-infrared fluorescent probes selectively binding to tau aggregates and method of preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2024-07-30 US disclosed
CN-117466815-A Synthesis method of azaanthrone compound 西北工业大学 2024-01-30 CN disclosed
CN-117024288-A Synthesis method of tomoxetine 迪嘉药业集团股份有限公司 2023-11-10 CN disclosed
CN-117024288-A Synthesis method of tomoxetine 迪嘉药业集团股份有限公司 2023-11-10 CN disclosed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP disclosed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO disclosed
CN-1044365-C Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis SANKYO CO (JP) 1999-07-28 CN disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
CN-1102640-A Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory and psychiatric disorders SANKYO CO (JP) 1995-05-17 CN disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12050224-B2 Compounds useful as near-infrared fluorescent probes selectively binding to tau aggregates and method of preparing the same MAPT, PSEN1, PSEN2 CCNB2 777/4885CDK1 637/4885CDK4 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.