⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411858 | 0.71 | — | — | |
| SCHEMBL3831848 | 0.71 | — | — | |
| SCHEMBL26373 | 0.67 | ALDH1A1 (0.56) | — | |
| SCHEMBL5778283 | 0.67 | — | — | |
| SCHEMBL3831840 | 0.67 | — | — | |
| SCHEMBL31311 | 0.67 | MAPT (0.39) | — | |
| SCHEMBL1395713 | 0.67 | — | — | |
| SCHEMBL25712 | 0.67 | MAPT (0.52) | — | |
| SCHEMBL395977 | 0.67 | MAPT (0.50) | — | |
| SCHEMBL231554 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056354-B2 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratinous fibers | L'OREAL (FR) | 2006-06-06 | — | — | US | claimed |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | L'OREAL (FR) | 2004-12-23 | — | — | US | claimed |
| US-6740655-B2 | 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 4-SPECIFIC INHIBITORS REDUCE EOSINOPHIL INFLUX TO THE LUNGS; SIDE EFFECT REDUCTION; ANTIINFLAMMATORY AGENT; ANTIALLERGENS; RESPIRATORY SYSTEM DISORDERS, ESPECIALLY ASTHMA | PFIZER INC | 2004-05-25 | — | — | US | claimed |
| US-20030144300-A1 | Pyrimidine carboxamides useful as inhibitors of pde4 isozymes | PFIZER PRODUCTS INC. | 2003-07-31 | — | — | US | claimed |
| US-20020169203-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-11-14 | — | — | US | claimed |
| EP-1252157-A1 | PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | Pfizer Products Inc. (US) | 2002-10-30 | — | — | EP | claimed |
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2001057025-A1 | PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER PRODUCTS INC. (US) | 2001-08-09 | — | — | WO | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |
| CN-118201913-A | Process for producing 2-heteroarylpyridine compound | 日本曹达株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-118139853-A | Process for producing 2-heteroarylpyridine compound | 日本曹达株式会社 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023090337-A1 | METHOD FOR PRODUCING 2-HETEROARYLPYRIDINE COMPOUND | 日本曹達株式会社 | 2023-05-25 | — | — | WO | disclosed |
| WO-2023090344-A1 | METHOD FOR PRODUCING 2-HETEROARYLPYRIDINE COMPOUND | 日本曹達株式会社 | 2023-05-25 | — | — | WO | disclosed |
| CN-110799868-B | Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device | 富士胶片株式会社 | 2022-02-22 | — | — | CN | disclosed |
| US-20020169203-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-11-14 | — | — | US | disclosed |
| EP-1252157-A1 | PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | Pfizer Products Inc. (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020013336-A1 | Fused heterocyclic compounds and their use in the treatment of neurodegenerative diseases | NEUROSEARCH A/S (DK) | 2002-01-31 | — | — | US | disclosed |
| WO-2001057025-A1 | PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER PRODUCTS INC. (US) | 2001-08-09 | — | — | WO | disclosed |
| EP-0231244-A1 | 6-ALKYLIDENE PENEMS | BEECHAM GROUP PLC (GB) | 1987-08-12 | — | — | EP | disclosed |
| WO-1987000525-A1 | 6-ALKYLIDENE PENEMS | BEECHAM GROUP P.L.C. (GB) | 1987-01-29 | — | — | WO | disclosed |