SCHEMBL13077081 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	PDF	Q9HBH1	10/20	0.77

▸	RAB9A	P51151	3/20	0.59

▸	MAPT	P10636	2/20	0.59

▸	KDM4E	B2RXH2	1/20	0.59

▸	MAPK1	P28482	1/20	0.59

▸	HKDC1	Q2TB90	1/20	0.59

▸	NPSR1	Q6W5P4	1/20	0.59

▸	TDP1	Q9NUW8	1/20	0.59

▸	KDM5A	P29375	1/20	0.56

▸	NPC1	O15118	5/20	0.46

▸	SMN1; SMN2	Q16637	2/20	0.46

▸	KMT2A	Q03164	2/20	0.43

▸	CA2	P00918	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL290235	0.87	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL10222557	0.86	PDF (0.76)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL289841	0.86	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL783241	0.81	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL290142	0.74	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL290072	0.74	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL299444	0.74	MAPT (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL290315	0.72	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL289618	0.72	PDF (1.00)	PDFRAB9AMAPTKDM4EMAPK1
SCHEMBL801217	0.72	KDM5A (1.00)	PDFRAB9AMAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010129049-A1	BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US)	2010-11-11	—	—	WO	disclosed