Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 7/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CDK11B | P21127 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.37 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.37 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.37 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120707 | 1.00 | TTK (0.47) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL120582 | 0.87 | BRD4 (0.51) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL120811 | 0.86 | BRD4 (0.53) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL6113177 | 0.86 | BRD4 (0.44) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL13077304 | 0.85 | TTK (0.47) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL123549 | 0.84 | BRD4 (0.47) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL123312 | 0.84 | BRD4 (0.49) | TTKBRD4IKBKBCDK11BCDK7 | |
| SCHEMBL120497 | 0.84 | EPHB4 (0.46) | TTKBRD4 | |
| SCHEMBL121029 | 0.83 | TTK (0.45) | TTKBRD4 | |
| SCHEMBL16882582 | 0.83 | TTK (0.45) | TTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424537-B1 | SUBSTITUTED IMIDAZOQUINOXALINES | BAYER IP GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| WO-2010124826-A1 | SUBSTITUTED IMIDAZOQUINOXALINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-04 | — | — | WO | disclosed |