Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 3/20 | 0.32 |
| ▸ | CHUK | O15111 | 2/20 | 0.32 |
| ▸ | CDK11B | P21127 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.32 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.32 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.32 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | BLK | P51451 | 1/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077306 | 0.88 | IKBKB (0.43) | TTKBRD4IKBKBCHUKCDK11B | |
| SCHEMBL121029 | 0.88 | TTK (0.45) | TTKBRD4PRF1 | |
| SCHEMBL16882582 | 0.88 | TTK (0.45) | TTKBRD4PRF1 | |
| SCHEMBL13077300 | 0.87 | BRD4 (0.43) | TTKBRD4IKBKBCHUK | |
| SCHEMBL13077299 | 0.86 | TTK (0.47) | TTKBRD4IKBKBCHUK | |
| SCHEMBL120707 | 0.85 | TTK (0.47) | TTKBRD4SYKIKBKBCDK11B | |
| SCHEMBL13077242 | 0.85 | TTK (0.47) | TTKBRD4SYKIKBKBCDK11B | |
| SCHEMBL13077297 | 0.82 | TTK (0.41) | TTKBRD4KDRCSF1RKIT | |
| SCHEMBL13077292 | 0.82 | RAB9A (0.42) | TTKBRD4KDRKIT | |
| SCHEMBL13077301 | 0.82 | FYN (0.42) | TTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124826-A1 | SUBSTITUTED IMIDAZOQUINOXALINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-04 | — | — | WO | disclosed |