Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.56 |
| ▸ | CNR1 | P21554 | 15/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078650 | 0.89 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL13079102 | 0.89 | CNR2 (0.54) | CNR2CNR1ALDH1A1 | |
| SCHEMBL13078648 | 0.84 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL13079095 | 0.83 | CNR1 (0.81) | CNR2CNR1 | |
| SCHEMBL13045545 | 0.83 | CNR1 (0.73) | CNR2CNR1 | |
| SCHEMBL1983424 | 0.80 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL13045552 | 0.79 | CNR1 (0.74) | CNR2CNR1 | |
| SCHEMBL1986649 | 0.79 | CNR1 (0.70) | CNR2CNR1 | |
| SCHEMBL13191019 | 0.78 | CNR2 (0.57) | CNR2CNR1ALDH1A1 | |
| SCHEMBL4974525 | 0.77 | CNR2 (0.71) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834046-B2 | Thiophene compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-11-16 | — | — | US | disclosed |
| US-20080090810-A1 | THIOPHENE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090810-A1 | THIOPHENE COMPOUNDS | CNR1, CNR2, HTR2C | CNR2 2/4885CNR1 1/4885ALDH1A1 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.