Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14819863 | 0.92 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL13045545 | 0.90 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL3740252 | 0.85 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL13079102 | 0.83 | CNR2 (0.54) | CNR1CNR2 | |
| SCHEMBL13045542 | 0.80 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL13078764 | 0.79 | CNR2 (0.56) | CNR1CNR2 | |
| SCHEMBL2849541 | 0.79 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL13045549 | 0.79 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL13045539 | 0.79 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL13045547 | 0.78 | CNR1 (0.73) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834046-B2 | Thiophene compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-11-16 | — | — | US | disclosed |
| US-20080090810-A1 | THIOPHENE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090810-A1 | THIOPHENE COMPOUNDS | CNR1, CNR2, HTR2C | CNR1 1/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.