Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399779 | 1.00 | DPP8 (0.51) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL27405538 | 0.87 | BIRC2 (0.44) | DPP8DPP9DPP7BIRC2DPP4 | |
| SCHEMBL27405539 | 0.87 | BIRC2 (0.44) | DPP8DPP9DPP7BIRC2DPP4 | |
| Hydrochloric Acid SCHEMBL15512436 | 0.86 | DPP8 (0.51) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL30064530 | 0.85 | DPP8 (0.47) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL13496274 | 0.84 | ERAP2 (0.54) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL19376936 | 0.83 | GSR (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL2115368 | 0.83 | GSR (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL17510190 | 0.83 | GSR (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL7781619 | 0.83 | GSR (0.58) | DPP8DPP9DPP7GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338643-B2 | Reagent for introduction of protein or gene | WASEDA UNIVERSITY (JP) | 2012-12-25 | — | — | US | disclosed |
| US-7838685-B2 | novel complex lipid having a cationic functional group derived from an amino acid; useful as a component of a stable, safe and functional carrier of a substance having an efficacy in pharmaceutical drugs, reagents, cosmetics and the like | Takeoka, Shinji (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | WASEDA UNIVERSITY (JP) | 2010-11-18 | — | — | US | disclosed |
| US-20090012306-A1 | Cationic Amino Acid Type Lipid | Takeoka, Shinji (JP) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | C1S, SGMS1, CERT1 | DPP8 4490/4885DPP9 4458/4885DPP7 4005/4885 |
| US-20090012306-A1 | Cationic Amino Acid Type Lipid | SLC7A1, NCEH1, DAO | DPP8 2930/4885DPP9 2246/4885DPP7 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.