Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386386 | 1.00 | NPC1 (0.57) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL6285826 | 0.94 | MAOB (0.59) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL2604702 | 0.91 | ABL1 (0.62) | MAPK1SMN1; SMN2ABL1ABCB1BCR | |
| SCHEMBL26784208 | 0.88 | ABL1 (0.62) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL4181089 | 0.87 | IDO1 (0.58) | TP53SMN1; SMN2IDO1CALM1 | |
| SCHEMBL27329 | 0.87 | IDO1 (0.58) | TP53SMN1; SMN2IDO1CALM1 | |
| SCHEMBL12040004 | 0.86 | NPC1 (0.47) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL13232533 | 0.85 | ABL1 (0.66) | RAB9AABL1ABCB1BCRMAOB | |
| SCHEMBL1477048 | 0.85 | IDO1 (0.56) | TP53SMN1; SMN2IDO1CALM1 | |
| SCHEMBL1475480 | 0.85 | IDO1 (0.56) | TP53SMN1; SMN2IDO1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833690-B2 | Photoacid generators and lithographic resists comprising the same | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2010-11-16 | — | — | US | disclosed |
| US-20070117043-A1 | Photoacid generators and lithographic resists comprising the same | NATIONAL SCIENCE FOUNDATION | 2007-05-24 | — | — | US | disclosed |